Still Stressed Out but Doing Fine

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Still stressed out but doing fine: normalization of wall stress is superfluous to maintaining cardiac function in chronic pressure overload.

Classically, myocardial hypertrophy is viewed as a long-term adaptive response of cardiac muscle to altered mechanical loading conditions, in which increasing wall thickness serves as the means to restore wall stress to normal, obeisant to the law of Laplace.1 The concept of local biomechanical stress as an instigator for this has been made clear through animal models, studies of cardiac muscle...

متن کامل

Stressed out and asthmatic

On page 157, Sarmento and colleagues show how the developmental regulator protein Notch1 advances the cell cycle. Activation of Notch1 induced the production of a protein that chops up cell cycle inhibitors, leading to a shortened G1 phase and a faster transition into S phase (but no overall increase in proliferation). The Notch family of transmembrane receptors regulates both cell fate decisio...

متن کامل

Telecardiology--close to the heart, but still out of reach.

legal consequences for both the patient and the consulting cardiologist. Enabling the consulting cardiologist to receive as many objective and imaging data as possible, in real time, is the perfect scenario. In this issue of IMAJ, Birati and Roth [3] review the latest data on the usefulness of telecardiology in various cardiac conditions. Although they focus on the Israeli experience and data, ...

متن کامل

Myocardial bridging and prognosis: more evidence but jury still out.

Myocardial bridging (MB) is a congenital variant of coronary anatomy in which a segment of a major epicardial coronary artery that normally has an epicardial course runs intramurally through the myocardium beneath the muscle bridge. It occurs most frequently in the mid-portion of the left anterior descending (Figure 1). It is also called ‘tunneled artery’. Geiringer first presented an in-depth ...

متن کامل

Stressed-out podocytes in diabetes?

Diabetic nephropathy is the most common cause of ESRD in the United States.1 Although current strategies can slow disease progression,2,3 development of renal failure requiring renal replacement therapy is a distressingly common outcome in patients with diabetes.1 As a result, much effort has been devoted to understanding the mechanisms that promote glomerular damage in diabetic kidney disease ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Circulation

سال: 2002

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circ.105.1.8